Eligard 22.5 mg (3-month) is supplied in two separate prefilled, sterile syringes whose contents are mixed immediately prior to administration. The two syringes are joined and the single dose product is mixed until it is homogenous. One syringe contains the Atrigel Delivery System, and the other contains leuprolide acetate. The Atrigel Delivery System is a polymeric (non-gelatin containing) delivery system consisting of a biodegradable, 45% poly (DL-Lactide-co-glycolide; PLG) polymer formulation dissolved in a biocompatible solvent, 55% N-methyl-2-pyrrolidone (NMP). PLG is a copolymer with a 75:25 molar ratio of DL-lactide to glycolide with hexanediol. The second syringe contains 28.2 mg lyophylized leuprolide acetate and is designed to deliver 22.5 mg of leuprolide acetate at the time of SC injection. Eligard 22.5 mg (3-month) is available in a single use pouch or tray packaging. The pouch and the tray packaging contain the two-syringe mixing system, a 20-gauge half-inch needle, and a silicone desiccant pouch (two for the tray packaging) to control moisture uptake.